Phenmetrazine (brand name Preludin, and many others) was a stimulant drug that was previously used as an appetite suppressant, but has since been withdrawn from the market. The drug had been widely abused. It was initially replaced by its analogue phendimetrazine (under the brand name Prelu-2) which functions as a prodrug to phenmetrazine, but now it is rarely prescribed, due to concerns of abuse and addiction.

Chemically, phenmetrazine is a substituted amphetamine with a morpholine ring.

Preludin was also used recreationally in the US throughout the 1960s and early 1970s. It could be crushed up in water, heated and injected. The street name for the drug in Washington, DC was “Bam”.

Phenmetrazine continues to be used and abused around the world.

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